Researchers have identified a specific protein responsible for melanoma metastasis that may provide an improved understanding of how the cancer spreads.
The study showed that silencing the expression of protein called RAB27A resulted in reduced metastasis – the process by which cancer spreads to other areas of the body – which is the primary cause of death in melanoma patients.
While there have been recent advances in targeted and immune-based treatments, advanced stage melanoma remains a clinical challenge with a particularly poor prognosis, suggests the study published in the International Journal of Cancer.