Manchester City displayed ruthless efficiency on Sunday to raise more questions over who can stop Pep Guardiola's team powering to a second straight English Premier League crown.
Raheem Sterling scored twice and goal-poacher Sergio Aguero was also on target as City marched back to the top of the standings with a 6-1 victory against Southampton at the Etihad Stadium.
Guardiola's players punished almost every mistake made in the opening stages by a beleaguered Southampton side as they led 3-0 after just 18 minutes.
The visitors pulled one back with a penalty but it proved a minor setback for City, which again dominated Southampton in the second half.
I thought it was a great team performance. We were brilliant at times today. It is great times at the moment.Raheem Sterling
In Sunday's other game, second-place Chelsea breezed past Crystal Palace 3-1 at Stamford Bridge.
Here’s a look at the big matches played in the last gameweek.
Manchester City Beat Southampton 6-1
City needed only five minutes to take the lead against Southampton, Wesley Hoedt putting through his own net following a neat move involving Aguero, David Silva and Leroy Sane.
Sterling then quickly laid on the second as Aguero became the ninth player to reach the landmark of 150 Premier League goals.
It was proving a nightmare return for Southampton manager Mark Hughes, who was in charge at City between 2008-09, as his side conceded a third goal when Sterling supplied a cross and David Silva lashed the ball home.
Southampton, without a win in six league games, replied in the 29th when Danny Ings was brought down in the box and picked himself up to stroke the penalty past goalkeeper Ederson.
But City restored their three-goal cushion on the stroke of half-time with Aguero taking advantage of a mistake by Cedric Soares and crossing for Sterling to get his fifth league goal of the season.
Sterling added his second of the game midway through the second half before Sane completed the rout in stoppage time.
We played excellently without, and especially with, the ball. We were aggressive in the final third, but we were lucky to score the goal in the last minute of the first half. The game was not over. Southampton created more chances than most teams this season.Pep Guardiola
Chelsea Beat Crystal Palace 3-1
Alvaro Morata continued his recent resurgence with two goals and fellow Spaniard Pedro added a third as Chelsea proved too strong for Roy Hodgson's Palace.
Unbeaten Chelsea made a slow start but Morata cheered the Stamford Bridge crowd by putting his side in front from close range in the 32nd after pouncing on a cross by Pedro.
Palace, beaten in their previous five league matches, leveled early in the second half when James McArthur sent Andros Townsend racing clear and he slammed a ferocious right-foot shot into the net.
Chelsea reacted by bringing on dangerman Eden Hazard and Mateo Kovacic for Willian and Ross Barkley, and within minutes the home team was back in front.
Hazard took a free kick on the right and the ball eluded several players in the penalty box before reaching the unmarked Morata at the back post, and he struck his fourth goal in his last four league games.
Pedro added the third goal from a left-wing cross by another Spaniard, Marcos Alonso, in the 72nd as Chelsea moved on to the same points tally as Liverpool, two behind City.
"We were a little bit in trouble, so we needed some quality and personality," Chelsea manager Maurizio Sarri said of his decision to bring on Hazard as a substitute. "We were lucky because we had Eden on the bench. He was able to immediately change the match.
In the first 15 minutes of the second half we were not compact. In the defensive phase we need to improve. When we can’t cover the ball in the opponent’s half we are in trouble.Maurizio Sarri
Arsenal Hold Liverpool 1-1
Liverpool midfielder James Milner's 50th English Premier League goal was not enough to secure victory as his side had to settle for 1-1 against fellow title chasers Arsenal at Emirates Stadium on Saturday.
The teams had first-half strikes ruled out for off-side and the visitors were particularly unfortunate to see Sadio Mane's effort disallowed.
The Senegal forward pounced after Roberto Firmino hit the post, and the goal was chalked off even though Mane was behind the ball when his fellow striker lobbed Arsenal goalkeeper Bernd Leno.
Alexandre Lacazette also netted at the other end but teammate Shkodran Mustafi was clearly in an offside position.
Liverpool eventually took the lead on the hour when Leno pushed Mane's cross back in front of his own goal and Milner drilled in his third goal of the season.
Alex Iwobi then set up the equalizer with a clever pass to Lacazette, who curled in a precise shot to preserve Arsenal's 14-match unbeaten streak in all competitions.
Manchester United Beat Bournemouth 2-1
Callum Wilson gave Bournemouth an early lead but United hit back against the run of play with a goal from Anthony Martial, his fifth in five games, in the 35th minute.
Substitute Marcus Rashford scored the winner two minutes into stoppage time at the end of the match after a surging run down the left and a pinpoint center from Paul Pogba.
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