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FAQ: WHO Approves China’s Sinovac Vaccine – How Effective Is It? 

Dubbed as CoronaVac, it is an inactivated vaccine, which is recommended for use in adults 18 years and older.

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The World Health Organisation (WHO) on Wednesday, 2 June, said it has approved a COVID vaccine by Sinovac Biotech for emergency use, making it the second Chinese shot to be given the green light.

"WHO today validated the Sinovac-CoronaVac COVID-19 vaccine for emergency use, giving countries, funders, procuring agencies, and communities the assurance that it meets international standards for safety, efficacy, and manufacturing," the WHO said in a statement.

Last month, Sinopharm became the first Chinese vaccine to be approved by the WHO.

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What is CoronaVac? Who is it for?

  • Dubbed as CoronaVac, it is an inactivated vaccine, which is recommended for use in adults 18 years and older, in a two-dose schedule with a spacing of two to four weeks.
  • Its easy storage requirements make it very manageable and particularly suitable for low-resource settings, the WHO said.

Which countries have given it emergency authorisation?

The COVID-19 vaccine has already been granted emergency authorisation in several countries including Indonesia, Turkey, Brazil, and Mexico.

What is CoronaVac’s efficacy?

  • The WHO said the efficacy results showed that the vaccine prevented symptomatic disease in 51 percent of those vaccinated and prevented severe COVID and hospitalisation in 100 percent of the studied population.
  • The WHO's strategic advisory group of experts on immunisation have reviewed the jab and published their advice on its usage.
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What are the concerns about the vaccine?

  • CoronaVac has battled concerns over its efficacy after the shot’s clinical trials across Brazil, Turkey, and Indonesia put the vaccine’s efficacy anywhere between 50 percent to over 90 percent, according to Bloomberg.
  • Researchers in Turkey said it is 91.25 percent effective in trials that included over 7,000 volunteers, but the efficacy result was based on data from 1,322 people, Reuters reported.
  • Indonesia said the vaccine is 65 percent effective, based on trials involving some 1,600 people.
According to experts, prevalence of the virus in each site, trial size, patient criteria, duration of post-vaccination observation, target groups among others could impact efficacy.

While the divergent efficacy rates have contributed to suspicions, evidence emerging in the real world is widely positive.

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What does the real world data from different countries suggest?

  • Last month, Indonesia said that its study of 1,30,000 healthcare workers in Jakarta who had received the vaccine found it was 94 percent effective at preventing symptomatic infection, and cuts hospitalisation and death by 96% and 98% respectively, rates comparable to mRNA vaccines, Bloomberg reported.
  • On Monday, 31 May, Brazil announced that a study in which an entire town received CoronaVac found that deaths from COVID had dropped by 95 percent.
  • Chile’s real-world data shows CoronaVac prevented 80 percent of deaths in those vaccinated and protected 67 percent from developing symptomatic infection.
  • Thus, the Sinovac shot is seen as highly effective in real world study.
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What does the WHO approval mean for countries worldwide?

WHO granting emergency use for CoronaVac paves the way for countries worldwide to quickly approve and import a vaccine for distribution.

The decision will allow CoronaVac to be used in WHO’s vaccine-sharing programme, COVAX, which seeks to provide equitable global access to immunisations, particularly in poorer countries.
  • WHO’s Emergency Use Listing (EUL) is a prerequisite for COVAX Facility vaccine supply and international procurement.
  • The WHO approval also paves the way for countries to allow travelers who have received Sinovac shots, even if the vaccine isn’t approved for use locally.

(This was first published on FIT and has been republished with permission.)

(At The Quint, we are answerable only to our audience. Play an active role in shaping our journalism by becoming a member. Because the truth is worth it.)

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Topics:  COVID-19   COVID-19 FAQ   coronavirus FAQ 

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